netmap.downstream.final_downstream¶

Functions

`compute_edge_overlaps_simple`	Compute the percentage of overlapping edges between a GRN and multiple reference networks.
`create_regulon_activity_adata`	Creates an AnnData object with regulon activity scores based on top GRN sources.
`curate_network`	Load CollecTRI data for a specific organism, format it, and curate the network data based on the provided gene regulatory network (GRN) data.
`filter_clusters_by_cell_count`	Filter features (genes/edges) based on cell count differences between two clusters, selecting the top fraction of features for each cluster.
`filter_grn_by_top_signatures`	Filters a GRN (Gene Regulatory Network) AnnData object to keep only the edges corresponding to the top-ranked signatures per cluster based on UCell scores.
`filter_signatures_by_Ucell`	Filters gene signatures by cluster and computes UCell scores.
`get_top_targets`	Selects top gene targets per source from a clustered gene interaction AnnData.
`plot_reg`
`plot_reg_curated`
`plot_shared_targets_heatmap`	Create a clustered heatmap showing shared target counts between sources.