netmap.downstream.final_downstream.compute_signatures_UCell_scores¶

netmap.downstream.final_downstream.compute_signatures_UCell_scores(selected_edges, adata, key='unique') → DataFrame¶

Filters gene signatures by cluster and computes UCell scores.

Parameters:

grn_adata (AnnData) – AnnData object containing GRN (gene regulatory network) information.
adata (AnnData) – AnnData object containing gene expression counts in the ‘counts’ layer.

Returns:

DataFrame with UCell scores merged with the ‘spectral’ cluster labels.

Return type:

pd.DataFrame